Research Paper Volume 15, Issue 19 pp 10213—10236

Icaritin ameliorates RANKL-mediated osteoclastogenesis and ovariectomy-induced osteoporosis

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Figure 3. ICT suppresses osteoclast function. (A) Representative images of F-actin rings. (B) Quantification of the F-actin rings number. (C) Mean number of nuclei in each cell. (D) Representative images of pit area by ICT-treated osteoclast on Osseo Assay plate. (E) Quantification of pit area. All data were presented as mean ± SD, n = 3. Abbreviation: ns: not statistical significance; *P < 0.05; ****P < 0.0001.