Figure 1. Construction and validation of an angiogenic prognostic model for grade 4 diffuse gliomas. (A, B) Lasso regression was used to screen angiogenesis-related prognostic genes in grade 4 diffuse gliomas. (C) Nomogram based on independent angiogenesis-related prognostic factors (COL22A1, IGFBP2, and MPO). (D–F) ROC curves for prediction of 1-year, 2-year, and 3-year OS by angiogenesis-related prognostic genes in grade 4 diffuse gliomas in TCGA database. (G) Time-dependent ROC-AUC with 95% confidence interval for 1-year, 2-year, and 3-year OS. X-axis time unit is day.