Hub gene identification and molecular subtype construction for <i>Helicobacter pylori</i> in gastric cancer via machine learning methods and NMF algorithm

Lianghua Luo; Ahao Wu; Xufeng Shu; Li Liu; Zongfeng Feng; Qingwen Zeng; Zhonghao Wang; Tengcheng Hu; Yi Cao; Yi Tu; Zhengrong Li

doi:doi:10.18632/aging.205053

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Research Paper Volume 15, Issue 21 pp 11782—11810

Hub gene identification and molecular subtype construction for Helicobacter pylori in gastric cancer via machine learning methods and NMF algorithm

Figure 4. Construction of the diagnostic nomogram on the basis of the twelve hub genes. (A) Venn diagram taking the intersection of the results of two ML strategies. (B) ROC curves measuring the diagnostic efficacy of the twelve HP-related hub genes. (C) Decision curve of nomogram graph. (D) Nomogram for the diagnosis of gastric cancer (GC). (E) Calibration curve demonstrating the diagnostic performance of the nomogram. (F) Clinical impact curve.