Research Paper Volume 15, Issue 19 pp 10089—10104

Eriocitrin inhibits epithelial-mesenchymal transformation (EMT) in lung adenocarcinoma cells via triggering ferroptosis

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Figure 5. Ferroptosis inhibitor Ferrostatin1 impeded the effects of eriocitrin on ferroptosis A549 and H1299 cells. (A) Fluorescent images of ROS in A549 and H1299 cells after treatment with 50 μM concentration eriocitrin, Fer-1, 50 μM concentration eriocitrin and Fer-1. (BE) Western blotting assay of ferroptosis related protein expression after Eriocitrin treatment. *P < 0.05, **P < 0.01, and ***P < 0.001. Abbreviation: Fer-1: Ferrostatin1.