Research Paper Volume 15, Issue 19 pp 10089—10104

Eriocitrin inhibits epithelial-mesenchymal transformation (EMT) in lung adenocarcinoma cells via triggering ferroptosis

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Figure 1. Eriocitrin treatment attenuated the viability and invasion of A549 and H1299 cells in a concentration-dependent manner. (A) The molecular structure of eriocitrin. (B, C) CCK8 assay. Cell viability of A549 and H1299 cells were measured after treatment of eriocitrin at various concentrations (0, 5, 10, 20, 40, 80, and 160 μM) for 24 h or 48 h. (D, E) Wound healing assay showed the migration ability of A549 and H1299 cells treated with eriocitrin at different concentrations (0, 25, 50, 75 and 100 μM) for 24 h or 48 h; (F, G) Wound closure ratio of A549 and H1299 cells after treatment with eriocitrin. *P < 0.05, **P < 0.01, and ***P < 0.001.