Research Paper Volume 15, Issue 18 pp 9521—9543
Construction of a novel cancer-associated fibroblast-related signature to predict clinical outcome and immune response in colon adenocarcinoma
Figure 7. Association of the CRFRs with the immune microenvironment of COAD. (A) Box plot showing differences in immune cells between the high- and low-risk subgroups using the CIBERSORT algorithm. (B) Box plot showing differences in immune-related functions between the high- and low-risk groups using the ssGSEA algorithm. (C–E) Stromal score, immunity score and ESTIMATE score in the two risk subgroups. (F) Histogram of proportions showing the proportion of patients with MSS, MSI-L and MSI-H in the high- and low-risk subgroups. (G) Box plot of differences in risk scores for patients in the MSS, MSI-L and MSI-H subgroups. (H) Box plot of TMB difference for the high- and low-risk subgroups. *P < 0.05, **P < 0.01 and ***P < 0.001.