Research Paper Volume 15, Issue 19 pp 10057—10071

Figure 8. The regulatory mechanism of LINC00667-miR-143-3p-ZEB1 axis on EMT. Caki cells were transfected using ZEB1 overexpression plasmids and/or miR-143-3p mimics, whereas A498 cells were transfected employing ZEB1-in and/or miR-143-3p-in. (A, B) The profiles of EMT markers tested by WB. [**P<0.01, ***P<0.001 (vs. NC or NC-in). ^^P<0.01, ^^^P<0.001 (vs. miR-143-3p/miR-143-3p-in)]. Caki cells were transfected with the addition of LINC00667 overexpression plasmids, miR-143-3p mimics, and/or ZEB1 overexpression plasmids, while A498 cells were transfected together with LINC00667-in, miR-143-3p-in and/or ZEB1-in. (C, D) The profiles of EMT markers were ascertained via WB. [***P<0.001 (vs. NC/NC-in). ^^P<0.01, ^^^P<0.001 (vs. LINC00667 or LINC00667-in). ns P>0.05, ##P<0.01 (vs. LINC00667+miR-143-3p or LINC00667-in+miR-143-3p-in). N=3.