Research Paper Volume 15, Issue 17 pp 9193—9216

Identification of a novel competing endogenous RNA network and candidate drugs associated with ferroptosis in aldosterone-producing adenomas

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Figure 4. WGCNA analysis and identification of hub modules related to the clinical traits. (A) Clustering dendrograms of samples and clinical traits of APA, age, gender, SBP, DBP, K, ALD and renin showed at the bottom. (B) Analysis of scale free network topology for various soft-threshold powers. The image on the left demonstrates the effect of soft-threshold power on the scale free topology model fit index; the right image shows the effect of soft-threshold power on the mean connectivity of the network. (C) Gene clustering dendrograms with dissimilarity based on the topological overlap, assigned with specific module colors. (D) The heatmap of correlation coefficient and p-value between modules and clinical traits. Each row represents a module, and each column corresponds to a clinical trait.