Research Paper Volume 15, Issue 17 pp 9167—9181

Human adipose-derived stem cells preconditioned with a novel herbal formulation Jing Shi attenuate doxorubicin-induced cardiac damage

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Figure 2. Jing Shi-preconditioned human adipose-derived stem cells (hADSCs) enhanced autophagy of doxorubicin-challenged H9c2 cells. The essential autophagic marker LC3B expression in Dox-challenged H9c2 cells was also exhibited lower expression. However, co-culture with hADSCs preconditioned with 50 or 100 μg/mL JS significantly induced the upregulated expression of LC3B in H9c2 cells. Scale bar was 100 μm.