Research Paper Volume 15, Issue 24 pp 14607—14616
The protective effects of Phoenixin-20 in tumor necrosis factor α (TNF-α)-induced cell senescence of rheumatoid arthritis fibroblast-like synoviocytes (FLS)
Figure 4. Phoenixin-20 ameliorated TNF-α-induced cellular senescence in RA-FLSs. RA-FLSs were stimulated with TNF-α (10 ng/mL) with or without Phoenixin-20 (10, 20 nM) for 7 days. Cellular senescence was assayed using SA-β-gal staining. Scale bar, 100 μm (※P < 0.01 vs. vehicle group; #, ##, P < 0.05, 0.01 vs. TNF-α group, N = 6).