Figure 3 — The protective effects of Phoenixin-20 in tumor necrosis factor α (TNF-α)-induced cell senescence of rheumatoid arthritis fibroblast-like synoviocytes (FLS)

Research Paper|Volume 15, Issue 24|pp. 14607–14616

The protective effects of Phoenixin-20 in tumor necrosis factor α (TNF-α)-induced cell senescence of rheumatoid arthritis fibroblast-like synoviocytes (FLS)

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Figure 3.Phoenixin-20 repressed the inflammation in TNF-α-treated RA-FLSs. RA-FLSs were stimulated with TNF-α (10 ng/mL) with or without Phoenixin-20 (10, 20 nM) for 24 h. (A) mRNA level of IL-1β, IL-6, and IL-8. (B) Protein level of IL-1β, IL-6, and IL-8 (^※P < 0.01 vs. vehicle group; ^#, ^##, P < 0.05, 0.01 vs. TNF-α group, N = 6).