Research Paper Volume 15, Issue 18 pp 9479—9498
Complement and coagulation cascades pathway-related signature as a predictor of immunotherapy in metastatic urothelial cancer
Figure 3. Association between the CCCP risk score and immune microenvironment in mUC and TCGA-BLCA cohort. (A) Comparison of immune cell infiltrations between patients with high- and low- risk score in mUC cohort. (B–E) Comparison of ssGSEA scores in immune checkpoint (B), T-cell receptor (C), T-effector and INF-γ (D) and tumor microenvironment (E) associated pathway between patients with high- and low-risk score. (F) GSEA enrichment analysis of T-cell receptor pathway and T-effector and INF-γ pathway in patients with high- and low-risk score. (G) Comparison of immune cell infiltrations between patients with high- and low- risk score in TCGA-BLCA cohort. mUC, metastatic urothelial carcinoma; CCCP, complement and coagulation cascades pathway; ssGSEA, single sample gene set enrichment analysis; GSEA, gene set enrichment analysis.