Research Paper Volume 15, Issue 17 pp 9059—9085
Prognostic and immunological roles of IL18RAP in human cancers
Figure 9. Downregulation of IL18RAP reduced the migration ability of M1 macrophages. (A–C) After transfection of HepG2, U251 and MDA-MB-231 with different siRNA, the IL18RAP protein levels was detected. (D) The induction process and morphology of M1 macrophages. (E) The schematic representation of the coculture of different cells. (F–I) The M1 macrophages’ migration after being cocultured with HepG2, U251 and MDA-MB-231 cells that have been transfected with si-IL18RAP-1, si-IL18RAP-2 or si-NC. *p < 0.05, **p < 0.01, ***p < 0.001.