Research Paper Volume 15, Issue 17 pp 9059—9085

Figure 6. The correlation analysis of IL18RAP expression and immune cells infiltration in pan-cancer. (A) The relationship between mRNA expression level of IL18RAP and infiltration of CD4+T cells, B cells, macrophages, CD8+T cells, dendritic cells and neutrophils in BRCA, LIHC, SARC, and SKCM was examed using TIMER algorithm. (B) Using the CIBERSORT algorithm, the relationship between IL18RAP expression and the infiltration of 22 different immune cell types in pan-cancer was determined. (C, D). Correlation of IL18RAP expression with the infiltration of CD8+T cells (C) and different kinds of macrophages (D) obtained from TIMER2.0 database. The results of M1 macrophages were circled in the black box. The results of M2 macrophages, CAFs, and MDSCs were circled in the red box.