Prognostic and immunological roles of IL18RAP in human cancers

Wu Chen; Tianbao Song; Fan Zou; Yuqi Xia; Ji Xing; Weimin Yu; Ting Rao; Xiangjun Zhou; Chenglong Li; Jinzhuo Ning; Sheng Zhao; Yuan Ruan; Fan Cheng

doi:doi:10.18632/aging.205017

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Research Paper Volume 15, Issue 17 pp 9059—9085

Prognostic and immunological roles of IL18RAP in human cancers

Figure 10. The construction of the PPI network and an analysis of IL18RAP's functional enrichment in cancers. (A, B) The PPI network (A) of IL18RAP constructed by Cytoscape, and the top 10 hub genes (B) of PPI were selected using cytoHubba plugins. (C) The correlation between the top 10 hub genes with IL18RAP in 33 types of cancers was calculated using Spearman correlation analysis. (D) The GO/KEGG enrichment analyses of the top 10 hub genes. (E) The relationship between IL18RAP and 10 famous cancer-related pathways was analyzed via GSCALite platform. The results of IL18RAP were circled in the black box.