Research Paper Volume 15, Issue 17 pp 8993—9021

Figure 6. Prognostic signatures construction and prediction. (A) Partial likelihood deviance of different numbers of variables. One thousand-fold cross-validation was applied for tuning penalty parameter selection. (B) LASSO analysis identified 11 CRGs. Each curve corresponds to one gene. (C) Risk score, distribution of patient survival status between the low- and high−risk groups, and expression heatmaps of 11 CRGs. (D) Kaplan–Meier curves indicated that there is a strong relationship between high and low risk score and the overall survival rate. (E) ROC curve was applied to assess the predictive efficiency of the prognostic risk signature.