Research Paper Volume 15, Issue 17 pp 8908—8929
TIMP1 shapes an immunosuppressive microenvironment by regulating anoikis to promote the progression of clear cell renal cell carcinoma
Figure 9. Down-regulation of TIMP1 suppressed the progression of ccRCC in vitro. (A) The expression of TIMP1 in A498 and 786-O cells was detected by RT-qPCR and Western blot; (B) TIMP1-knockdown suppressed ccRCC cell proliferation in A498 and 786-O cells; (C) Wound-healing tests demonstrated changes in ccRCC cell migration; (D) TIMP1-knockdown suppressed ccRCC cell metastasis in A498 and 786-O cells.