Research Paper Volume 15, Issue 17 pp 8908—8929
TIMP1 shapes an immunosuppressive microenvironment by regulating anoikis to promote the progression of clear cell renal cell carcinoma
Figure 7. Identification the immune infiltration characteristics of TIMP1 in ccRCC. (A–C) The differential expression of immunosuppressive cells between high and low TIMP1 groups (A) MDSC; (B) Macrophage; (C) Regulatory.T.cell; (D) The correlation of TIMP1 expression profile with immune cells in ccRCC; (E–G) The differential expression of tumor microenvironment scores between high and low TIMP1 groups (E) ImmuneScore; (F) StromalScore; (G) ESTIMATEScore; (H–J) The differential expression of immune checkpoints between high and low TIMP1 groups (H) CTLA4; (I) CD96); (J) PDCD1; (K) The correlation of TIMP1 expression profile with immunosuppressive checkpoints in ccRCC.