Research Paper Volume 15, Issue 17 pp 8908—8929

TIMP1 shapes an immunosuppressive microenvironment by regulating anoikis to promote the progression of clear cell renal cell carcinoma

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Figure 3. Establishment and prognostic features of Anoikis index. (A, B) Lasso analysis of prognostic ARGs with minimum lambda value; (C) The risk curve of each sample reordered by AI and the scatter plot of the sample survival overview. The blue and pink dots represent survival and death, respectively; (D) The distribution of anoikis-related genes expression profile and clinicopathological characteristics in AI; (E) Overall survival curve showing the prognostic difference between high and low AI group; (F) ROC curves about AI in 1,2,3 years; (G, H) The univariate and multivariate Cox regression analysis of AI, age, gender, grade, stage, TMN stage; (I) Differences in survival between high and low AI groups in the E-MTAB-1980 cohort; (J) ROC curves about AI in 1,2,3 years in the E-MTAB-1980 cohort.