Research Paper Volume 15, Issue 19 pp 10031—10056

Huangqi Guizhi Wuwu decoction promotes M2 microglia polarization and synaptic plasticity via Sirt1/NF-κB/NLRP3 pathway in MCAO rats

class="figure-viewer-img"

Figure 5. HGWD promoted dendritic spine density and synaptic plasticity. (A) Examples of dendritic spines. Scale bar=10 μm. (B) Density of dendritic spines. (C) Representative western blot bands of PSD95 and synapsin I in each group. (D, E) The quantitative analysis of PSD95 and synapsin I expression in hippocampus. ##P < 0.01 vs. control group; *P< 0.05, **P< 0.01 vs. model group.