Figure 5 — Huangqi Guizhi Wuwu decoction promotes M2 microglia polarization and synaptic plasticity via Sirt1/NF-κB/NLRP3 pathway in MCAO rats

Research Paper|Volume 15, Issue 19|pp. 10031–10056

Huangqi Guizhi Wuwu decoction promotes M2 microglia polarization and synaptic plasticity via Sirt1/NF-κB/NLRP3 pathway in MCAO rats

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Figure 5.HGWD promoted dendritic spine density and synaptic plasticity. (A) Examples of dendritic spines. Scale bar=10 μm. (B) Density of dendritic spines. (C) Representative western blot bands of PSD95 and synapsin I in each group. (D, E) The quantitative analysis of PSD95 and synapsin I expression in hippocampus. ^##P < 0.01 vs. control group; *P< 0.05, **P< 0.01 vs. model group.