Research Paper Volume 15, Issue 16 pp 8315—8324
miR-100-5p activation of the autophagy response through inhibiting the mTOR pathway and suppression of cerebral infarction progression in mice
Figure 3. Overexpression of miR-100-5p decreased the protein expressions of phosphorylated mTOR and total mTOR but increasing the expression of autophagy-related proteins Beclin, LC-3II, and ATG-7 in vivo. (A) Representative Western blot images. (B) Column comparison of the relative expression of proteins. mTOR, mammalian target of the rapamycin; LC-3II, microtubule-associated protein light chain 3II; ATG-7, autophagy-related gene 7; NC, negative control; KD, knock down; OE, overexpression. *P<0.05, **P<0.01. NS: irrelevant.