Research Paper Volume 15, Issue 16 pp 8298—8314
Gastrodin ameliorates cognitive dysfunction in diabetes by inhibiting PAK2 phosphorylation
Figure 6. Gastrodin intervention and PAK2 inhibition restored the expression of PI3K/AKT/GLUT4 pathway in the primary hippocampal neurons exposed to high glucose. Double immunofluorescence staining of PI3K, p-AKT and GLUT4with NeuN in the primary hippocampal neurons of NC (A), DM (B), DM+G (C) and DM+I (D) groups. Bar = 50 μm.