Research Paper Volume 15, Issue 16 pp 8185—8203

Figure 1. (A) Landscape plot of the effect of 18 prognosis-related stem gene sets in breast cancer on survival of BC patients. Cluster 1, orange; cluster 2, blue; HR>1 is Cluster 1, HR<1 is Cluster 2; circle size represents significance. The lines connecting gene sets represent cellular interactions. The thickness of the line represents the strength of correlation. Positive correlation is indicated in red and negative correlation in light blue. (B) KM curves for OS of breast cancer patients from TCGA and METABRIC cohort. (C) Sankey plot showing the relationship between SGS grouping and IHC typing as well as PAM50 molecular typing. (D) Box plot showing the correlation between SGS and IHC subtypes of breast cancer patients. (E) Box plot showing the correlation between SGS and PAM50 molecular typing of breast cancer patients. (F) Heatmap manifesting the relationship between SGS groupings and clinical pathological parameters in the TCGA.