Research Paper Volume 15, Issue 16 pp 8113—8136
Comprehensive characterization of pyroptosis phenotypes with distinct tumor immune profiles in gastric cancer to aid immunotherapy
Figure 7. Characteristics of the pyroptosis score in molecular subtypes and tumor genome somatic mutations. (A, B) GSEA showing the activated signaling pathways in samples with high and low pyroptosis scores in the gastric cancer meta-cohort. (C, D) Mutational landscape in TCGA-STAD cohort clustered by high and low pyroptosis score subgroups. (E) Relative distribution of SCNA in high and low pyroptosis score groups from TCGA-STAD cohort. (F) Relative distribution of pyroptosis score in different molecular subtypes (MSI-H, MSI-L and MSS) in TCGA-STAD cohort. (G) Relative distribution of MSI status in patients with high and low pyroptosis scores from TCGA-STAD cohort.