Research Paper Volume 15, Issue 16 pp 8090—8112
Identification of immunotherapy biomarkers for improving the clinical outcome of homologous recombination deficiency patients with lung adenocarcinoma
Figure 5. Relationship between MS4A6A expression pattern and TIME. (A) MS4A6A expression is positively correlated with ImmuneScore (Spearman rank correlation coefficient, R = 0.83, P ≈ 0). (B) MS4A6A expression is positively correlated with neoantigen load (Spearman rank correlation coefficient; P < 0.05). (C) MS4A6A expression was positively correlated with immune cell subpopulation (Spearman rank correlation coefficient; P < 0.0001). (D) MS4A6A expression is positively correlated with antigen-related genes. (E) Correlation of MS4A6A expression signature with antigen-related genes in the TCGA pan-cancer cohort.