Research Paper Volume 15, Issue 16 pp 8044—8060

Figure 8. GLP-1 represses inflammatory response in LPS-mediated RAW264.7 cells. (A) Cell viability. The mRNA expression level of iNOS (B), COX-2 (C), IL-1β (D), IL-6 (E), and TNF-α (F) in LPS-induced RAW264.7 cells. The protein expression of iNOS (G, H) and COX-2 (G, I) was estimated by western blotting. The values shown here are the mean ± SD of three independent experiments. For LPS+GLP-1 induced RAW264.7 cells vs. the LPS group, ^*p < 0.05 - ^**p < 0.01 and for LPS-induced RAW264.7 cells vs. the NT group, ^#p < 0.05 was considered significant.