Research Paper Volume 15, Issue 17 pp 8630—8663

Prognostic model of kidney renal clear cell carcinoma using aging-related long noncoding RNA signatures identifies THBS1-IT1 as a potential prognostic biomarker for multiple cancers

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Figure 3. Construction of prognostic model using feature genes. (A) Identification of optimal gene set for the signature of CarLncs subgroups based on the SVM-RFE algorithm. (B) Top thirty genes with the highest “MeanDecreaseGini” for the optimal RF model. (C) Venn diagram of the overlapped genes of the two algorithms; (D) Independent prognostic factors for developing the aging related prognostic model were identified by Cox HR model.