Research Paper Volume 15, Issue 15 pp 7593—7615
Development of tryptophan metabolism patterns to predict prognosis and immunotherapeutic responses in hepatocellular carcinoma
Figure 9. Analysis of four TRPGs for the prognostic signature, and their correlations of tumor immune infiltrating cells and therapeutic drugs. (A)The boxplot showed the relationship among ACSL3, ADH1B, ALDH2, and HADHA expression and grade stratification. (B) The boxplot depicts the correlation of ACSL3, ADH1B, ALDH2, and HADHA expression and T stage. (C) The correlation of five TRPGs and TME score. (D) The relationship between five TRPGs and 23 activated immune cells. (E) The correlation of four TRPGs and immune checkpoints. (F) The relationship between four TRPGs and common therapeutic drugs for HCC. *p<0.05, **p < 0.01. TRPGs, tryptophan metabolism-related genes; TME, tumor microenvironment.