Research Paper Volume 15, Issue 15 pp 7593—7615

Development of tryptophan metabolism patterns to predict prognosis and immunotherapeutic responses in hepatocellular carcinoma

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Figure 8. Correlations of tumor immune cell microenvironments and two TRPGs prognostic subtypes. (A) GSVA of biological pathways between two risk groups, in which red represent activated and blue inhibited pathways, respectively. (B) Heatmap of the clinicopathologic characteristics and tumor-infiltrating cells in the two risk groups. (C) Expression abundance of 23 infiltrating immune cell types in the two risk subtypes. (DF) Correlations between the TME score and the two risk subtypes. (G) Expression of immune checkpoints between the two risk subtypes. *p<0.05, **p < 0.01, ***p < 0.001. TRPGs, tryptophan metabolism-related genes; GSVA, gene set variation analysis; TME, tumor microenvironment.