Research Paper Volume 15, Issue 15 pp 7593—7615

Development of tryptophan metabolism patterns to predict prognosis and immunotherapeutic responses in hepatocellular carcinoma

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Figure 3. Clinicopathological features, enrichment analysis and mutation landscape of two TRPGs clusters. (A) Differences in clinicopathologic characteristics and expression levels of TRPGs between the two subtypes. (B) GSVA of biological pathways between two subtypes. (C) GO enrichment analysis showing the BP, CC, and MF of two TRGs subtypes. (D) The bubble plot depicted the KEGG pathway enrichment analysis of the two clusters. (E) Mutation landscape of TRPGs cluster A. (F) Mutation landscape of TRPGs cluster B. GSVA, gene set variation analysis; GO, gene ontology; BP, biological process; CC, cellular component; MF, molecular function; KEGG, Kyoto Encyclopedia of Genes and Genomes; TRPGs, tryptophan metabolism-related genes.