Research Paper Volume 15, Issue 15 pp 7593—7615
Development of tryptophan metabolism patterns to predict prognosis and immunotherapeutic responses in hepatocellular carcinoma
Figure 10. Validation of the four prognostic genes in functional analysis and clinical data. (A) The colony formation and migration analysis of LM3 cell depletion with ACSL3, ADH1B, ALDH2, and HADHA. (B) Immunohistochemistry analysis of ACSL3, ADH1B, ALDH2, and HADHA in HCC tissues. (C) The high expression level of ACSL3 and the low expression level of ALDH2 and HADHA were associated with a poor prognosis. The Cox proportion hazards model was used to understand the significance between the two groups.