Research Paper Volume 15, Issue 15 pp 7533—7550
HBx promotes hepatocellular carcinoma progression by repressing the transcription level of miR-187-5p
Figure 2. HBx inhibited the expression of miR-187-5p. (A) Decreased expression of miR-187-5p in hepatocellular carcinoma identified by UALCAN database. (B) Decreased expression of miR-187-5p by RT-qPCR detection in Huh-7 and HepG2 cells. (C) HBx overexpression significantly reduced miR-187-5p expression by RT-qPCR. (D) The expression of miR-187-5p decreased with the increase of HBx expression. The experiments were repeated at least 3 independent times. *p < 0.05; **p < 0.01; ***p < 0.001.