Research Paper Volume 15, Issue 14 pp 7187—7218

Identification of TGF-β-related genes in cardiac hypertrophy and heart failure based on single cell RNA sequencing

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Figure 8. Six hub genes and corresponding transcriptional factors. (A) t-SNE plot showing the expression characteristic of the six hub genes in the control and heart failure samples. (B) Heatmap showing the expression of six hub genes in each cell type. (C) Relative mRNA expression of the six hub genes in the 2w TAC model. * P < 0.05. (D) Heatmap showing the expression of differentially expressed transcriptional factors in each cell type. (E) Transcriptional factor and hub gene regulatory network. (F) Correlation diagram between MYC and ADAMTS2.