Research Paper Volume 15, Issue 14 pp 7023—7037
Single-cell transcriptomics reveals the drivers and therapeutic targets of lymph node metastasis in lung adenocarcinoma
Figure 5. Validation of pro-LNM signature associated with LNM and prognosis in the TCGA LUAD cohort. (A) An overview of the association between the pro-LNM signature and clinicopathological parameters of LUAD patients. Columns showed patients ranked by pro-LNM signature from low to high (top row), and other rows represented the clinicopathological features. (B) Associations between pro-LNM signature and N staging in the TCGA LUAD cohort. (C) K-M survival analysis revealed significantly poorer OS in patients with high levels of pro-LNM signature. Abbreviations: LNM: lymph node metastasis; TCGA: The Cancer Genome Atlas; LUAD: lung adenocarcinoma; OS: overall survival.