Figure 4. Platelet-related scores (PRS) were an unfavorable factor in LUSC. (A) The cluster 3 with worst outcomes had higher PRS. (ANOVA test, p < 0.001). (B) OS analysis for the LUSC patients with high- and low-PRS. (HR = 1.6). (C) The HR and p-value of PRS and 50 Hallmark pathways. (D) ROC curves for 2-, 4-, and 6-year. (E) PCA displayed the distribution of the two subclusters. (F–H) LUSC patients with high PRS tended to have a bad prognosis in GEO database (GSE3141, GSE12472 and GSE30219).