Research Paper Volume 15, Issue 13 pp 6545—6576
Comprehensive prognostic and immunological analysis of Ubiquitin Specific Peptidase 28 in pan-cancers and identification of its role in hepatocellular carcinoma cell lines
Figure 4. The landscape of genetic alterations of USP28 in pan-cancer. (A) The alteration frequency with the mutation type of USP28 for the TCGA tumors was analyzed by the cBioPortal tool. (B) The protein domain displayed all the mutation sites and mutation types of USP28. (C) The highest alteration frequency (R204*/G) was shown in the 3D structure of USP28 (labeled in yellow). (D–F) The potential correlation between alteration status of USP28 and clinical prognostic indices, including overall survival, disease-free survival, and progression-free survival in specific cancers.