Figure 1. Expression and variation profiles of 12 cuprotosis-related genes in AML patients. (A) Location of CNV of 12 Cuprotosis genes on chromosomes. (B) Expression of 12 cuprotosis-related genes in AML patients with different risk stratification. (C) Heat map of cuprotosis-related genes in AML patients and normal population. (D) Difference in the expression level of cuprotosis-related genes between normal and tumour samples. (E) CNV frequency of Cuprotosis genes, the copy number amplification, green dot; the copy number deletion, red dot. (F) Mutation frequency of 12 cuprotosis-related genes in 130 samples. (*P < 0.05, **P < 0.01, ***P < 0.001).