Research Paper Volume 15, Issue 13 pp 6445—6466

Figure 9. Patients with high-risk and low risk scores have different immune statuses. PCA maps show the distribution of patients based on the (A) whole genome; (B) cuproptosis-related gene sets; (C) cuproptosis-related lncRNAs; and (D) the predictive signature. Results for ssGSEA scores immune cells scores (E) and immune functions scores (F) between high and low risk groups in boxplots. Abbreviations: PCA: Principal component analysis; lncRNAs: long noncoding RNAs; ssGSEA: single-sample gene set enrichment analysis. aDCs: activated dendritic cells; iDCs: immature dendritic cells; NK: natural killer; pDCs: plasmacytoid dendritic cells; Tfh: T follicular helper; Th1: T helper type 1; Th2: T helper type 2; TIL: tumor-infiltrating lymphocyte; Treg: T regulatory cell; APC: antigen-presenting cell; CCR: chemokine receptor; HLA: human leukocyte antigen; MHC: major histocompatibility complex; IFN: interferon.