Research Paper Volume 15, Issue 13 pp 6400—6428

Figure 8. The expression and clinicopathological classifications of TIGD1 in TCGA-COAD cohort. (A) Venn plot. Kaplan-Meier survival analysis for five CDM-associated genes in in TCGA–COAD and GSE17536 cohort. Blue represents TCGA-COAD and yellow represents GSE17536 cohort. (B, C) Violin plot. The mRNA expression of TIGD1. Red represents tumour and blue represents normal. (B) for TCGA-COAD dataset (p<0.0001). (C) for TCGA-COAD and GTEx dataset (p<0.001). (D) Violin plot. Correlation between tumour stage and TIGD1 expression in TCGA-COAD cohort. Pink represents I stage, green represents II stage, Cyan represents III stage and violet represents IV stage (p<0.01). (E) Violin plot. Correlation between lymph node metastasis (N) and TIGD1 expression in TCGA-COAD cohort. Pink represents N0 (not metastasis), blue represents N1 (1-3 regional lymph node metastases) and cyan represents N2 (4 or more regional lymph node metastases) (p<0.01). (F) Violin plot. Correlation between metastasis (M) and TIGD1 expression in TCGA-COAD cohort. Pink represents M0 (not metastasis), blue represents M1 (metastases) (p<0.05). (G) Violin plot. Correlation between depth of tumor invasion (T) and TIGD1 expression in TCGA-COAD cohort. Pink represents T1, blue represents T2, Cyan represents T3 and violet represents T4 (p>0.05).