Research Paper Volume 15, Issue 13 pp 6400—6428
Exploring Cancer Dependency Map genes and immune subtypes in colon cancer, in which TIGD1 contributes to colon cancer progression
Figure 11. WGCNA analysis, consensus clustering and immune subtype construction. (A) Module–Clinical Trait Relationships of consensus module eigengene and different clinical features of COAD. Each row in the table corresponds to a module eigengene (ME), and each column to a clinical parameter (five module: blue, red, black and grey; eight clinical features: Age, Gender, Stage, T, N, futime, fustat and CDM riskScore). Each cell contained the correlation coefficients and p value (red, positively correlated; green, negative correlated). (B) Venn plot of CDM-associated co-expressed genes (5,662 genes) and upregulated genes (8,179 genes). Red represents coexpressed genes and cyan represents TCGA-COAD upregulated genes. (C) The consensus score matrix of TCGA-COAD samples when k = 2. Subtype A contains 306 samples and subtype B contains 143 samples. (D) The consensus score matrix of GSE39582 samples when k = 2. Subtype A contains 382 samples and subtype B contains 203 samples.