Research Paper Volume 15, Issue 13 pp 6302—6330

Clinical significance, tumor immune landscape and immunotherapy responses of ADAR in pan-cancer and its association with proliferation and metastasis of bladder cancer

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Figure 5. Involvement of ADAR in tumor immune response. (AD) ADAR is positively correlated with the expression of chemokines, chemokine receptors, HLAs, and tumor necrosis factors (TNF) in most cancers. (E) Correlation analysis between ADAR and ICIs. (F) ADAR and TMB achieved high positive correlation in THYM, ACC, LUAD, STAD, LGG, COAD, KICH, CHOL, SARC, and BLCA. (G) ADAR was significantly associated with MSI in READ, LAML, COAD, GBM, UVM, CESC, UCEC, LUSC, BLCA, and LIHC.