Review Volume 15, Issue 13 pp 6577—6619

Crosstalk between m6A and coding/non-coding RNA in cancer and detection methods of m6A modification residues

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Figure 4. Crosstalk of m6A and miRNAs. m6A can modulate miRNA processing, maturating, or pre-miRNA splicing via “Writers” or “Readers” to inhibit or promote cancers. miRNAs regulate m6A regulators by sponging to affect m6A modification, suppressing or promoting cancers. Abbreviations: OV: ovarian cancer; BCA: bladder cancer; CRC: colorectal cancer; HCC: hepatocellular cancer; PDAC: pancreatic ductal adenocarcinoma; BC: breast cancer; GBM: glioblastoma; NSCLC: non-small cell lung cancer.