Research Paper Volume 15, Issue 13 pp 6179—6211

Figure 9. Corrections of ZNF765 expression with m⁶A modification in HCC. (A) The correlation between ZNF765 expression and the expression of m6A-modified genes was investigated by the Spearman statistical method using the TCGA and ICGC databases. (B) Distinct m6A-related gene expression in HCC patients with different expressions of ZNF765. (C) Five genes were found at the intersection of the TCGA and ICGC databases. (D) A Western blot was used to detect ZNF765, RBMX, and HNRNPA2B1 protein expression in HCCLM3 cells stably transfected with the control shRNA or the ZNF765 shRNA. (E) The correlation between ZNF765 and m⁶A-modified genes was analyzed by the scatter plot. (F) The overall survival of HCC patients was separated into two groups based on the high and low expression of these five m⁶A genes. ^*p < 0.05; ^**p < 0.01; ^***p < 0.001.