Research Paper Volume 15, Issue 12 pp 5592—5610

Significance of liquid-liquid phase separation (LLPS)-related genes in breast cancer: a multi-omics analysis

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Figure 3. Construction and validation of the prognostic model. (A) Univariate COX analysis of intersection genes. (B, C) Prognostic model was established by Lasso regression. (D) Survival analysis of TCGA cohort. The LLPS_high group had a significantly worse prognosis (p<0.0001). (E) LLPS score was higher in dead patients of TCGA cohort. (F) Principal component analysis (PCA). (G) The prognostic model can divide breast cancer patients into two groups well. (GI) External independent cohort verification.