Figure 3. Molecular subtypes based on 10 DRG in the meta cohort. (A) Unsupervised consensus clustering based on 10 DRG for 1155 HCC patients in a meta cohort (GSE14520, GSE36376, GSE76427, LIRI-JP, and TCGA-LIHC). (B) Kaplan-Meier curve showed a significant difference between the 2 DRG.clusters. (C) PCA analysis between 2 DRG.clusters. (D) The different genes between the 2 DRG.clusters. (E) The univariate Cox regression analysis between 40 DEGs and overall survival. (F) GO enrichment analysis, (G) KEGG enrichment analysis for the DEGs and prognosis genes between the 2 DRG.clusters.