Research Paper Volume 15, Issue 12 pp 5399—5411
Comprehensive analysis reveals the involvement of hsa_circ_0037858/miR-5000-3p/FMR1 axis in malignant metastasis of clear cell renal cell carcinoma
Figure 8. Identification of a potential hsa_circ_0037858/miR-5000-3p/FMR1 axis contributing to metastasis of ccRCC. The regulatory role of hsa_circ_0037858/miR-5000-5p in FMR1 expression in ACHN (A) or Caki-1 (B). The inhibition of hsa_circ_0037858 in in vitro migration could be reversed by miR-5000-3p overexpression in ACHN (C, D) and Caki-1 (E, F) cell lines (G) The action model of hsa_circ_0037858/miR-5000-3p/FMR1 axis in metastasis of ccRCC. **P<0.01; ***P<0.001; ****P<0.0001.