Research Paper Volume 15, Issue 11 pp 5144—5163

Network medicine framework identified drug-repurposing opportunities of pharmaco-active compounds of Angelica acutiloba (Siebold & Zucc.) Kitag. for skin aging

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Figure 3. The 8 AAK compounds had potential pharmacologic efficacy for skin aging. (A) The shortest, closest and |z-shortest| calculated between compounds and skin aging by proximity and LCC analysis; (B) ROC curve of the 8 AAK compounds to skin aging and therapeutic diseases).