Research Paper Volume 15, Issue 11 pp 5125—5143

Network pharmacology-based research on the effect of angelicin on osteosarcoma and the underlying mechanism

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Figure 12. The effect of angelicin on the expression of hub target genes in osteosarcoma MG63 cells. The mRNA expression of the hub genes in osteosarcoma MG63 cells was measured after 24 h of culture with media containing different concentrations (0 μmol/ml, 50 μmol/ml, or 200 μmol/ml) of angelicin; (A) BAX, (B) Casp9, (C) BIRC2, (D) Bcl2; ns (No significance): No statistically significant difference between the two groups. When P < 0.05, *the difference between the two groups is statistically significant. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.