Research Paper Volume 15, Issue 11 pp 5052—5065
Regulation of endothelial ferroptosis by SESN1 in atherosclerosis and its related mechanism
Figure 7. Overexpression of SESN1 inhibited ferroptosis in ox-LDL-induced HUVECs via activating P21. (A) Immunofluorescence was used to detect the iron metabolism in vascular tissues. (B) The expressions of SESN1, P53, P21 and ferroptosis-related proteins were detected by western blot. *P < 0.05, ***P < 0.001 vs. Model; ###P < 0.001 vs. Model+UC2288; $P < 0.05, $$P < 0.01, $$$P < 0.001 vs. Ov-SESN1+Model.