Research Paper Volume 15, Issue 11 pp 5052—5065
Regulation of endothelial ferroptosis by SESN1 in atherosclerosis and its related mechanism
Figure 4. Overexpression of SESN1 increased cell activity and inhibited cellular inflammation and oxidative stress responses in ox-LDL-induced HUVECs. (A) CCK8 was used to detect the cell activity. (B) ELISA was used to detect the levels of inflammatory factors in cells. (C) The kits were used to detect the expression of oxidative stress-related factors ROS, MDA and GSH. ***P < 0.001 vs. Control; #P < 0.05, ###p < 0.001 vs. Ov-NC+Model.